FOIA "There is evidence of toxicity to nasal epithelial cells with alcohol, benzalkonium chloride, and concentrations of povidone-iodine above 2.5%," Barone says. , Frank Please enable it to take advantage of the complete set of features! Improved antisepsis of human and nonhuman surfaces has been identified as a key feature of transmission reduction. A total . Epub 2020 Jun 16. the. CofixRX (povidone-iodine) was developed by a team of eight board-certified doctors. We propose in this SBIR Phase I to optimize an in-situ gel forming nasal spray formulation containing both povidone iodine and budesonide by using polysaccharide gel matrix, where the effective concentrations of drug substances are maintained by the equilibrium between solution drug substances and the gel bound components resulting in a long . Michael Menna, DO, is currently an attending emergency medicine physician at White Plains Hospital in White Plains, New York, with nearly 10 years of experience. Oral and nasal sprays with antiviral activity against SARS-CoV-2, for example, are actively being studied. 10% Povidone Iodine is available OTC (Over the Counter) without a Can You Drink Alcohol After Getting the COVID-19 Vaccine? 8600 Rockville Pike An official website of the United States government. Data Sharing Statement: See Supplement 2. All Rights Reserved. NF, Klatt-Cromwell Front Line Doctors Ivermectin Protocol for Prevention and Treatment of COVID-19 (November 2022), 12 Natural Treatments for COVID Long Haulers (2023). (2021, July 19). Lim NA, Teng O, Ng CYH, Bao LXY, Tambyah PA, Quek AML, Seet RCS. doi: 10.1177/0145561320977784. mortality drug league table below. Brown SM, et al. The application of povidone-iodine to large wounds or severe burns may produce systemic adverse effects such as metabolic acidosis, hypernatraemia and impairment of renal . According to the researchers: Halodine Nasal Antiseptic: Spray: 1.25 g/100mL: Topical: Halodine LLC: 2021-02-01: Not applicable: US: Halodine Nasal Antiseptic . Epub 2008 Apr 18. All Rights Reserved, McCullough et al. Figure 96.2. Rapid In-Vitro Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Using Povidone-Iodine Oral Antiseptic Rinse. Stathis C, Victoria N, Loomis K, Nguyen SA, Eggers M, Septimus E, Safdar N. Future Microbiol. 2022 Oct;74(Suppl 2):2906-2911. doi: 10.1007/s12070-021-02525-9. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Ingesting povidone-iodine can pose health risks. Procedures: Three groups received liposomal dispersion with PVP-I (2.2, 4.4 and 0% as control) in single and repeated use (3 days, three times a day). Find many great new & used options and get the best deals for (2) CofixRX Nasal Spray Povidone Iodine 1.25% Nasal Spray Xylitol FREE SHIP at the best online prices at eBay! doi: 10.3205/dgkh000416. Have a question, send us a message at info@viraldine.com or, 1565 Pennsylvania Avenue, Box 285, Pine City, New York 14871, United States. News-Medical.Net provides this medical information service in accordance Germs spread from person to person mainly in droplets that fly out when you cough or sneeze. Clipboard, Search History, and several other advanced features are temporarily unavailable. Price and other details may vary based on product size and colour. More specifically, an Intranasal Povidone-Iodine (PVP-I; 1.25%) spray has been found to be active against SARS-CoV-2, as well as SARS-CoV and the Middle East Respiratory Syndrome (MERS). These results were similar to PVP-I . Doctors don't recommend the general use of Betadine to prevent or treat COVID-19. Epub 2021 Apr 8. A, Cheng Potassium iodate and/or potassium iodide 0.05-2.5%. Rev. Image: Associate Professor Peter Friedland, from UWA's Medical School, was lead author of the study. Epub 2020 Sep 19. 2021;57:39-45. doi:10.1016/j.jdsr.2021.03.001, Teikai T, Takada A, Hasebe A, Kajihara M, Okuya K., et al. Results: . PMC Careers. HHS Vulnerability Disclosure, Help This formulation will not only ensure patient comfort but also it will have the advantage of dual antiviral action with BAK and PVP-I [24]. Guenezan J, Garcia M, Strasters D, et al. Epub 2022 Sep 9. Researchers and doctors around the . THROAT SPRAY. FOIA In Vitro Efficacy of a Povidone-Iodine Nasal Antiseptic for Rapid Inactivation of SARS-CoV-2. A recent study published in PLOS One estimated the virucidal efficacy of Essential Iodine Drops (EID) for oral/nasal decontamination of known or suspected cases of COVID-19 as a potentially better alternative to the PVP-I. Debprasad Chattopadhyay, a biomedical scientist (Citations: 5140, h-index: 40; i-10 Index: 99; ORciD: 0000-0002-7999-329X; Scopus ID: 7102873753; 2nd among top ten Scientists of ICMR) and among top 2% Global Scientist, completed his Post-Graduation in 1983, and PhD (Science) from Jadavpur University in 1989. Guenezan J, Garcia M, Strasters D, et al. About Mundipharma, When povidone iodine, the active ingredient in, Kills 99.99% of sore throat-causing Viruses and bacteria in as early as 30 seconds, M093P020123BS, M081P021323BS, M076P021023BS. Keywords: Researchers discovered that there was a SARS-CoV-2 viral load reduction in all individuals from the 2021 study. Povidone-iodine is in the well-known antiseptic, Betadine. Both the PI . DIY 1% Povidone Iodine. C, Schneider Direct to throat delivery. Watch Video Tutorial Here: 1% Povidone Iodine DIY How To Video. Povidone-iodine has been used as an antiseptic by surgeons and other professionals for many years. Viraldine is USP Povidone Iodine nasal spray without damaging surfactants. 28 Clinically, chronic topical use of concentrations up to 5% when used daily have been demonstrated to not result in thyroid disease. Efficacy of Mouth Rinses and Nasal Spray in the Inactivation of SARS-CoV-2: A Systematic Review and Meta-Analysis of. In March 2020, the Agency published three guidance documents to provide . with the formulations described in these . All Rights Reserved. JS, Tessema Preclinically, it has been evaluated for . You should send a copy of this article to Boris (PM). Prophylaxis is not that hard. Posted in: Medical Research News | Disease/Infection News | Pharmaceutical News, Tags: Allergic Contact Dermatitis, Coronavirus, Coronavirus Disease COVID-19, Coughing, covid-19, Decontamination, Dermatitis, Efficacy, in vivo, Maxillofacial, Respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Skin, Sneezing, Surgery, Syndrome, Thyroid, Virus. Iodine 1% Nasal Spray is part of the FLCCC I-CARE early treatment protocol : Nasal spray with 1% povidone-iodine: 2-3 times a day. Humco 232516001 Povidone Iodine 10% Topical Solution, 16 oz. For those of us who are not chemistry majors:HOW do you make a solution with 200 micrograms per milliliter??? 4.6 4.6 out of 5 stars (1,375) $26.04 $ 26. , Pennington JS. Performance assessment of SARS-CoV-2 PCR assays developed by WHO referral laboratories. S, Brown Indian J Otolaryngol Head Neck Surg. Use 1 % povidone iodine commercial . HC. Her work consisted of functionalizing nanoparticles with different molecules of biological interest, studying the reaction system and establishing useful applications. Accessibility Viraldine LLC - 1565 Pennsylvania Avenue, Box 285, Pine City, NY 14871 -1-866-259-6863. When used as a preoperative antiseptic in oral and maxillofacial surgery, for example, PVP-I is often associated with late-onset allergic contact dermatitis in some patients due to the free iodine that has an oxidizing effect on the skin or mucosa. Nasodine Nasal Spray is based on povidone-iodine, the same active ingredient found in Betadine throat gargle, and has been in development for almost a decade as a treatment for the common cold. Purpose of study: A method of treating a disorder mediated by BRD9 comprising administering an effective amount of a compound of Formula: or a pharmaceutically acceptable salt thereof Taken together, the current study concluded that being excipient-free, Iodine-V is likely to have better stability and an enhanced potency in vivo when compared with PVP-I against SARS-CoV-2. between patient and physician/doctor and the medical advice they may provide. (Amazon), Amazon Basic Care Premium Saline Nasal Moisturizing Spray, Pre-hospital use of Corticosteroids in COVID-19, Miraculous Recovery of Hypoxemic COVID-19 Patients with Ivermectin, Paxlovid (Pfizer) vs Ivermectin vs Molnupiravir (Merck), Dr Peter McCullough Early Treatment Protocol (December 2022), America's Frontline Doctors Early Treatment Protocol and Contact a Physician 2023, How to Make Povidone Iodine 1% Nasal Spray, Find a Doctor to prescribe Paxlovid, Hydroxychloroquine, Ivermectin and Early Outpatient Treatments, Quercetin and Zinc: Zelenko Treatment Protocol, FLCCC I-CARE COVID Treatment Protocol for Outpatients (2023). The PVP-I complex. This COVID-19 Vaccine Is the First Plant-based Vaccine for Humans. Study: Efficacy of Essential Iodine Drops against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2). B. Ear Nose Throat J. We use cookies to analyze website traffic and optimize your website experience. USP PVP-I, Moisturizing USP 1% Povidone Iodine Nasal Spray & Throat Spray, Treat The Cause & Relieve Symptoms from Allergies, Chronic Sinusitis, Cold, Flu, Viral Infections, Head & Sinus Pain & Pressure, USP Povidone Iodine Nasal Sprays in .5% 1% & 1.5% Formulas. Read our. Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19): A Review. Limitations include the small number of patients and the single-center design. Epub 2022 May 6. Dwivedi, Ramya. VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE VIRALDINE, VIRALDINE Povidone Iodine is a disinfectant, and you want the solution, not the scrub. PVP-I solutions used for disinfection of the skin or wounds have a 1% iodine content. Cold and Flu Products, 2021 MUNDIPHARMA | : BETADINE is a Registered Trademark OF MUNDIPHARMA. Ashley Abramson is a freelance writer based in Milwaukee, WI. The preparation method of povidone iodine: be that 1.17% potassium iodide is dissolved in . No clinically relevant changes in mucosa appearance, nor in olfactory sense, nor in ciliary activity (sensitive indicator of local tolerance) occurred and no complaints about nasal airflow obstruction were observed. Renessans Helps in Early Clearance of SARS-CoV-2: Use of Saline Nasal Irrigation (Jala Neti) in SARS-CoV-2 Infection and its Complications Like Mucormycosis Needs to be Given a Serious Consideration. Intervention consisted of 4 successive mouthwashes and gargles with 25 mL of 1% aqueous PI solution each (Mylan, Merignac, France), followed by one 2.5-mL nasal pulverization of the same solution into each nostril using an intranasal mucosal atomization device (MAD Nasal, Teleflex, Morrisville, North Carolina) connected to a 5-mL syringe while sniffing and 1 application on each nasal mucosa of a dab of 10% PI ointment followed by a massage of the nostril to help spread the ointment. Mean relative difference in viral titers between baseline and day 1 was 75% (95% CI, 43%-95%) in the intervention group and 32% (95% CI, 10%-65%) in the control group (Figure). 1. In this work, Dr. Knts found that Iodine-V, which is currently available as the EID formulation, inactivated 99% of SARS-CoV-2 after 60 and 90 seconds. There was no financial compensation for these contributions. Zarabanda D, Vukkadala N, Phillips KM, Qian ZJ, Mfuh KO, Hatter MJ, Lee IT, Rao VK, Hwang PH, Domb G, Patel ZM, Pinsky BA, Nayak JV. Povidone iodine is an over-the-counter (OTC) medication applied on the skin. Add to List. - Tilt head back, apply 4-5 drops to . . A clinical study on the tolerability of a liposomal povidone-iodine nasal spray: Implications for further development. Considerations for povidone-iodine antisepsis in pediatric nasal and pharyngeal surgery during the COVID-19 pandemic. JA, Westover 2022. National Library of Medicine Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. Early treatment using this approach is associated with a 71% improvement, as shown in the figure. Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients? Introduction: Chumpitaz-Cerrate V, Chvez-Rimache L, Ruiz-Ramirez E, Franco-Quino C, Erazo-Paredes C. J Int Soc Prev Community Dent. Povidone-iodine Recommendation of the German Society of Hospital Hygiene (DGKH): Prevention of COVID-19 by virucidal gargling and virucidal nasal spray - updated version April 2022. 2 There is an urgent need to develop other affordable and readily available strategies . News-Medical. Methods: Povidone iodine nasal antiseptic formulations and PVP-I oral rinse antiseptic formulations from 1% to 5% concentrations as well as controls were studied for virucidal efficacy against the SARS-CoV-2. %PDF-1.6 % MeSH Between 2023 and 2027, the market is . Small Business. Povidone Iodine nasal spray and throat spray helps cleanse away allergens, germs, viruses & bacteria to relieve symptoms from infections, chronic sinusitis & allergies. Available in 50mL. Once within the nose, throat, and mouth, they multiply and grow and they are then inhaled and cause excess mucus. However, this is based on only 1 JA. EPOTHEX Povidone Iodine Nasal Spray (0.6%) - Powerful Nasal Cleanser & Sinus Protection - Reduce Exposure to Airborne Contaminants - Travel Friendly - 30ml. If too much is swallowed, you'll need to seek medical attention or contact a Poison Control Center. While mitigation measures such as lockdowns, masking, social distancing, and vaccines have been adopted to reduce the transmission of SARS-CoV-2, several other methods of reducing and controlling the virus have been proposed. A total of 4 patients (33%) in each group were male. April 14, 2020. Please note that medical information found CONCLUSIONS AND MESSAGE: Application of liposomal PVP-I spray to the nasal mucosa does not result in any demonstrable limitation of the nasal function nor in detectable damage to the multilayer ciliated epithelium of the nose. Correctives 0.1-3%. Unable to load your collection due to an error, Unable to load your delegates due to an error. Povidone iodine. "After a 25-minute contact time, the nasal spray reduced virus from 4.2 to 1.7 log10 CCID50 per 0.1 Read more 19 Best Quercetin and Bromelain Benefits 2023. One misinformed trend, gargling Betadine to prevent COVID-19 infection, allegedly started on Twitter. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). This single-center, open-label randomized clinical trial with a 7-arm parallel-group design was conducted in Dhaka Medical College (DMC) Hospital. There are also medicated douchesmade with 0.3% povidone-iodineto help relieve minor vaginal irritation and itching. Federal government websites often end in .gov or .mil. Study significance. These tiny drops from a person move through the air and land on the mouths or noses of others nearby. 2021;132,(11):2089-2095. doi:10.1002/lary.29935. With topical use. The study was approved by the South Mediterranean Institutional Review Board, and written informed consent was obtained from all participants. Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic. Before The Povidone-Iodine Solution from up & up is used to disinfect and clear out small cuts and wounds, and the dark brown liquid dyes the skin so you can better see what you're up against. Concept and design: Guenezan, Garcia, Lvque, Frasca, Mimoz. Accessibility Statement, Our website uses cookies to enhance your experience. 2022 Oct;74(Suppl 2):3534-3535. doi: 10.1007/s12070-022-03149-3. Unable to load your collection due to an error, Unable to load your delegates due to an error. Practical use of povidone-iodine antiseptic in the maintenance of oral health and in the prevention and treatment of common oropharyngeal infections. The https:// ensures that you are connecting to the EID, for example, is an aqueous solution of Iodine-V containing 200 micrograms (g) of elemental iodine/milliliter (ml). Some of the information and statements contained in this website have not been fully evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure or prevent any disease, nor are they intended to be a substitute for one-on-one professional medical advice, diagnosis or treatment. Gently blow nose to clear both nostrils. 2021 Jan;16(2):119-130. doi: 10.2217/fmb-2020-0286. 2021;147(4):400401. Find patient medical information for povidone-iodine oral mucous membrane on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. While the current study established that EIDs are as efficacious as PVP-I against SARS-CoV-2, it also discussed it as a potentially safer alternative to PVP-I, as this agent is known to cause serious rashes despite being non-cytotoxic. Published Online: February 4, 2021. doi:10.1001/jamaoto.2020.5490. Endocrinology, a medicinal branch that deals with endocrine and metabolic disorders, is witnessing cutting-edge drug research to develop advanced drugs that can treat diabetes, obesity, hypoparathyroidism and other disorders.The endocrinology market is witnessing impressive growth it is growing at a compound annual growth rate (CAGR) of 7.82 percent. Pfizer is in early-stage talks to acquire cancer-focused biotech Seagen for over US$ 30 billion. A panel of external experts to the US Food and Drug Administration (FDA) has backed both GSK and Pfizer's respiratory syncytial virus (RSV) vaccines, setting the stage for a tight race between the two to become the first approved US shot against the disease.After the recent enactment of the . Nasodine is a commercial formulation of 0.5% PVP-I that has been evaluated for safety and efficacy in human trials as a treatment for the common cold, including a Phase III trial (ANZCTR: ACTRN12619000764134). When To Get Boosted After Having a COVID-19 Breakthrough Infection, Omicron Infection Timeline: When Symptoms Start and How Long They Last. Safe and effective for peace of mind. Benefits and safety of nasal saline irrigations in a pandemicwashing COVID-19 away. In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies. The https:// ensures that you are connecting to the The nasal spray will disinfect areas unreachable by gargling. This site needs JavaScript to work properly. "We have now recognized C 19 is a viral infection in the nose and mouth for 3 to 5 days before it invades the body. Betadine also has an antiseptic throat gargle made with 0.5% PVP-I, but it's only meant to treat and relieve symptoms of a sore throat. on this website is designed to support, not to replace the relationship A review of iodine toxicity reports. endstream endobj 229 0 obj <. as 30 seconds.85, Helps relieve 7 signs and symptoms of a sore throat.113, 5 benefits in 1 - Scientifically demonstrated to kill common viruses, bacteria, fungi, spores and microscopic parasites that causes sore.85,114,.115. Povidone iodine nasal antiseptic formulations and PVP-I oral rinse antiseptic formulations from 1% to 5% concentrations as well as controls were studied for virucidal efficacy against the SARS-CoV-2. Critical revision of the manuscript for important intellectual content: Guenezan, Garcia, Strasters, Jousselin, Lvque, Frasca. An oro-nasal spray is designed to apply the PVP-I in the nose and oral cavity to gain a protective layer or coating over nasal . They looked at the evidence of the gargle's virus-killing aspects in relation to COVID-19. PMC Viraldine povidone iodine nasal spray is made using only USP ingredients which ensures the highest quality formulas available. However, a limitation of this study was that there was no control group for the study and that the findings might be more suited for short-term use by medical providersnamely, dentists or physicians who needed to perform an oral examination. All Rights Reserved. Comparison of In Vitro Inactivation of SARS CoV-2 with Hydrogen Peroxide and Povidone-Iodine Oral Antiseptic Rinses. Safe and effective for peace of mind. A spring 2020 study by United Kingdom researchers recommends that health care professionals and COVID-19 patients use the solution as a nasal spray and a mouthwash. Dent. 3. There is, of course, another danger too: It's that people are using remedies like povidone-iodine instead of the vaccinewhich is proven to work. If 1% product is not available, dilute the more widely available 10% solution and apply 4-5 drops to each nostril every 4 hours. 1997;195 Suppl 2:93-9. doi: 10.1159/000246039. Since it doesn't contain alcohol or hydrogen peroxide, povidone iodine shouldn't sting when it's applied to the wound. 2020 Nov;99(9):586-593. doi: 10.1177/0145561320932318. It's not clear where the idea that Betadine could potentially prevent COVID-19 came from in the first place. The use of Povidone Iodine nasal spray and mouthwash during the current COVID-19 pandemic for the reduction of cross infection and protection of healthcare workers. 2022 Oct 31;12(5):488-499. doi: 10.4103/jispcd.JISPCD_65_22. Procedures: If 1% product is not available, dilute the more widely available 10% solution and apply 4-5 drops to each nostril every 4 hours. A, Escuret The best, safest evidence-based methods for preventing COVID-19 (and staving off severe disease and hospitalization) remain to be vaccination and masking. Dwivedi, Ramya. sharing sensitive information, make sure youre on a federal The 200 ppm hand sanitizer is extremely effective, and we highly recommend it. POVIDONE IODINE NASAL SPRAY & throat spray for Allergy, Cold Flu & Viral Symptoms. Dr Peter McCullough: Nasal Spray and Mouth Gargle to stop COVID? https://www.news-medical.net/news/20210719/Iodine-derivative-kills-SARS-CoV-2-within-90-sec.aspx. Dr. Domb says to mix half a teaspoon of the 10% Povidone Iodine solution with a 44-mL spray bottle of saline nasal . 2020;146(11):1-5. doi:10. . Test compounds were evaluated for ability to inactivate SARS-CoV-2 as measured in a virucidal assay. , Krber Explanation could be humidification, improved surfactant (phospholipid) level and/or sufficient mucolytic activity of iodide due to local application of the constituents. And he hasn't returned so doesn't know of the now 2 comments awaiting his response. Iodine is established as having a broad-spectrum antimicrobial activity against bacterial, viral, fungal, and protozoal pathogens and has been used as an antiseptic for the prevention of infection and the treatment of wounds for decades.. 2022 Sep 13;12(9):1424. doi: 10.3390/life12091424. Zoltn Knts, a researcher from IOI Investment Zrt., in Budapest, Hungary, recently demonstrated the efficacy of iodine against SARS-CoV-2 as a better alternative to Povidone-Iodine. No other disclosures were reported. (2021) Efficacy of Essential Iodine Drops against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2). The formula of povidone iodine: the mass percent of each component consists of: polyvinylpyrrolidone k30:20.0%, iodine: 4.3%, potassium iodide 3.11%, solvent normal propyl alcohol: 23.0%, stability auxiliary agent: 8.0%, surplus is water.