Learn More. If you have been looking into hair loss treatments or are just looking at increasing your hair density, then youve probably heard about Minoxidil and Nanoxidil. After several more years of development, they landed on what we know as minoxidil. However, the drug will only be approved by FDA for the treatment of androgenetic alopecia after its long-term effects have been studied. Minoxidil killed my cat. Avoidance is the best plan. We also use third-party cookies that help us analyze and understand how you use this website. As a treatment for hair loss, Minoxidil works by using potassium channel openers (PCOs). This makes blood flow much improved in the area and thereby increases nutrients to the hair follicles. Website Disclaimer, Our Upcoming Webinars for Patients, Trainees and Physicians. display: block !important; This should theoretically lead to a better penetration and absorption rate. It was developed back in the 50s. There are no other topical treatments FDA approved at the present time. This means that these molecules force the channels to be more open, enlarging the hair follicle, which plays a large part in the better results for thinning hair. Minoxidil's molecular weight is 209.25 g/mol while in nanoxidil it's 195.22 g/mol. Veterinarians confirmed pulmonary edema and pleural effusions. My GF has two catsI don't worry about it. Prostaglandins for Hair Growth: A Potential Hair Loss Treatment? line-height: 1.2em; https://e-aaps.org/journal/view.php?number=293. Apply the prescribed amount of solution directly from the dropper to the scalp. Keeping medicine safely stored away can prevent many tragedies. All Rights Reserved. The other benefit of nanoxidil is that it will not affect any other hormonal activity in your body, which is why hair growth stimulated by nanoxidil is longer and stronger. I have 2 and I just cant take that risk. (2016). Most of what is needed though is just common sense. However, there is limited scientific evidence of the efficacy of nanoxidil. Minoxidil topical solution (Rogaine) is a hair loss treatment drug used to stimulate the hair follicles in your scalp. Getting minoxidil from Keeps is very simple with their online interface, and you can choose between solution or foam. But if the results of these few studies hold up in future trials, we could definitively say that nanoxidil is superior to minoxidil. This category only includes cookies that ensures basic functionalities and security features of the website. This field is for validation purposes and should be left unchanged. That gives it a lower molecular weight and an extremely slight size advantage over minoxidil. If using foam, apply the foam to your fingers first. .fak-back { display: none;} There is no need to dilute it with any kind of water or the use of droppers. Watch for failure to eat, vomiting, difficulty breathing or lethargy. It contains 5% nanoxidil and compounds such as caffeine, adenosine, azelaic acid, copper tripeptide, and retinol, which have a synergistic effect with nanoxidil. DNC-N significantly reduced hair shedding, with a corresponding increase in hair mass and density. If you are worried about applying Minoxidil on your scalp then you will find Nanoxidil to be much easier to use. Studies are still underway, and they may reveal other side effects which are currently not yet identified. That cat had trouble breathing, high heart rate, water in the lungs (pulmonary edema and pleural effusion) and showed increased liver enzymes. You also dont want to go to bed before your application has a chance to dry completely, which takes about four hours. Spectral.DNC-N is the first topical hair-loss treatment to employ 5% Nanoxidil, a powerful new alternative to Minoxidil, a compound with high efficacy, low molecular weight, and no known side effects. All Rights Reserved. Minoxidils molecular weight is 209.25 g/mol while in nanoxidil its 195.22 g/mol. Creatine Causes Hair Loss. Initial signs of lethargy generally begin within 12 hours and heart damage occurs 3-4 days . It was later on put under Rogaine for commercial purposes. Its overall an effective form of hair loss treatment, and its especially recommended towards people who have tried topical Minoxidil and failed to see any hair regrowth. I'd heard it was dangerous to cats, so I kept the bottle tightly closed and in a drawer when not using, and washed my hands thoroughly after using. By clicking Accept, you consent to the use of ALL the cookies. IMO your cat is in just as much more danger from clothes detergent than minoxidil. The catagen hair implant has been more effective than this kind by introducing tension that you can feel every time you move your head. Minoxidil killed my cat. What is DNC-Nano? Nevertheless, this fact also means much less in terms of side effects for this treatment. No portion of this page may be duplicated without consent. display: block !important; These hairs are resting, but are not shed. According to the study, a 5% dosage was applied twice daily by men and women with androgenetic alopecia over a period of 12 months. On the plus side, it can be used by both men and women. You can't be too careful, and just because they aren't showing any symptoms yet doesn't mean they won't. Take the same general precautions you would with . Minoxidil exposure can result in lethargy, hypotension, pulmonary edema, damage to the heart muscle and death from cardiac failure. Prior to that, my routine had been minoxidil foam (on crown and hairline areas -- morning and night) + finasteride 1 mg daily. Still, early studies look favorably on nanoxidil, with no reported adverse effects from using nanoxidil. A full head of strong, thick hair is considered a symbol of good health. Approximately 85% of hair on your head is in this stage. Moreover, Rogaine treatment may be required for several months before it shows any results. These include headaches, heart problems, local irritation at the application site, and the possible development of acne. Unfortunately, cats lack the specific enzyme necessary to break down this drug making them more susceptible to toxicity than dogs. Nanoxidil will remain active in your body for the entire time you want it to and will continue stimulating hair growth until you discontinue the therapy, unlike minoxidil. While recovering from Minoxidil toxicity, feed your cat often and encourage him or her to eat well. You also have the option to opt-out of these cookies. Effects of a New Topical Treatment Containing Several Hair Growth Promoters in Women with Early Female Pattern Hair Loss. That cat died 10 hours later despite supportive care.Several other cases of minoxidil toxicity have been reported to various animal poison control centers. It is a special type of hair band that is attached to your real hair. Information about side effects of minoxidil and nanoxidil. The majority of subjects in the study experienced noticeably good results, and only 3 % of women saw no change after a 6-month treatment period. Other ingredients: azelaic acid, retinol, caffeine, tri-copper peptides, lecithin, adenosine, and others, Suitable for sensitive skin no PG (propylene glycol). You can rely on medical treatments that have been specially formulated for hair loss, such as minoxidil. It may take up to 9-12 months of regular application for satisfactory results. If hair growth is going to occur with the use of minoxidil, it usually occurs after the medicine has been used for several months and lasts only as long as the medicine . Some would even spend their life savings to restore a full head of hair. The drug once introduced made some changes in the hair loss industry. Minoxidil is a potassium channel opener that is commonly used in the treatment of high blood pressure (hypertension). Christopher hopes everyone can learn from both his experience and research. https://www.researchgate.net/publication/316087773/. It is used for treatment of male- and female-pattern hair loss. If you do not keep taking it, you will lose all of your progress. Some of our partners may process your data as a part of their legitimate business interest without asking for consent. Published 2015. As mentioned, Minoxidil is excellent to use no matter why you are losing your hair. Absorption and drying take up to four hours. It can probably even be used by children whose hair is receding. If you notice any other effects, check with your healthcare professional. The content of this website is intended to provide accurate, up-to-date and scientifically-based information on all aspects of hair loss. However, the drug was not originally intended to work on hair. Amaryllis. Spectral.DNC-N, with Nanoxidil, contains powerful antioxidants and anti-inflammatory peptides that can improve overall scalp health. It was intended to treat high blood pressure by lowering your cholesterol. It is also often used together with the stimulation technique that is used with the device such as the HairMax laser comb. Treatment is often symptomatic depending on the symptoms and condition of the pet. Nevertheless, the study had various limitations, such as the absence of a placebo or control group to which the results could be compared. Minoxidil was the first drug to be clinically proved as an agent to grow hair. By the age of 50, approximately 50% of women and 85% of men experience some degree of hair loss, which according to the size of the U.S. population translates into 84 million women and 137 million men! It is best to consult your doctor before committing to the treatment. If you would like to try it, you can always make a purchase from one of the major drug stores, online stores, or visit the DS Laboratories in 1601 Green Rd, Pompano Beach, Florida. Only limited research is available on the efficacy and safety of nanoxidil or its usefulness in comparison with minoxidil. Minoxidil exposure can result in lethargy, hypotension, pulmonary edema, damage to the heart muscle and death from cardiac failure. } (1)(2)(3). article p{ Studies that have been conducted on the efficacy of topical minoxidil have revealed that it has the capability to work in two primary ways. It may not display this or other websites correctly. .blog-title { Caster Bean . :stupid: Well Rabid, remember it's not too late to kill them. Keeps also provides its patients with free access to their prescribing physician through a simple messaging interface. In case of a medical concern or emergency, please consult your healthcare provider. For example, a 2% solution would be gentler than a 5% solution on your skin. Cats lack an enzyme to break down minoxidil. If you struggle with hair loss, youre not alone. Olsen EA; Dunlap FE; Funicella T; Koperski JA; Swinehart JM; Tschen EH; Trancik RJ; A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men. (6) This can further cause scalp itching and inflammation, among other symptoms. Minoxidil was the very first drug that was introduced in the market for hair growing purposes. Save my name, email, and website in this browser for the next time I comment. Upon returning to the home, the owners found the cat also having difficulty breathing. Home Care and Prevention There is no home care for Minoxidil toxicity. But opting out of some of these cookies may have an effect on your browsing experience. F; V-GSC. Half of all men will experience some form of hair loss before they reach 50. To avoid any serious side effect, it should only be used by the recommendations of a physician. The DHT is the hormone that causes hair loss in men and Regaine prevents the hair from thinning and hair loss by working on the DHT. However, Spectral.DNC-N is a new player on this market that definitely stands out from the rest. Hair fibers are products that are specifically meant for those people who are suffering from hair loss. Telogen effluvium is non-scarring hair loss that typically happens after a traumatic event causes a "shock" to the body's system. I bought the 5% solution from my local pharmacy and started using it. Im a young guy who is passionate about helping guys get the most out of life. The most recent study on nanoxidil was an uncontrolled clinical trial conducted in 2018. http://dogsofsf.com/wp-content/uploads/ G_2407.jpg, Shiseido to Begin Cell Hair Regeneration Trial, Kyocera to Begin Regenerative Hair Loss Treatment Research. The drug was successively found to successfully promote hair growth in men and has since been used extensively by men and women experiencing balding. It was found that minoxidil was able to stimulate the growth of hair when applied on the scalp daily. Minoxidil is considered a first-line treatment to aid hair growth, but it shows inconsistent efficacy. In fact, a placebo works better in women than minoxidil for hair growth. One of the latest new hair growth building concepts is the catagen implant. However, if you are starting on hair loss treatment, then nanoxidil is a reasonable option. Moreover, no follow-up studies were done to evaluate the long-term effects of nanoxidil. Telogen Effluvium happens when the hair enters into the resting phase and the hair follicles cease to grow. Despite most people giving attention mostly to the topical formulations, studies now show that oral minoxidil could, Read More Oral Minoxidil for Hair Loss: Better than Topical?Continue, Studies regarding the use of prostaglandin analogues for the treatment of hair loss disorders are promising. The prevailing theory is that it allows more oxygen, nutrients, and blood to reach your follicles than would otherwise be the case. Read More Clascoterone (Breezula): a Novel Hair Loss Treatment?Continue, RU58841 is a non-steroidal antiandrogenic medication that was initially developed in the 1980s as a topical treatment remedy for, Read More RU58841 for Hair Loss Underused Finasteride Alternative?Continue. This happens naturally, without affecting your hormones. To correct these shortcomings of minoxidil, Divine Skin Inc., a cosmeceutical company, released an alternative called Spectral DNC-N. Many of the people suffering from hair loss would give almost anything to reverse it. Doctors often recommend minoxidil for balding at the crown or vertex; receding hairlines often fail to respond to it. 24-11-2022 Es el segundo bote que compro, as que he repetido, creo que me va bien . Thanks for your feedback. According to a 2009 KoreMed study, topical nanoxidil in a 5% solution was used. This drug works by enlarging a few blood vessels in the body to help increase blood flow. Brijesh Patel DS Healthcare Group Inc Maria Abril Martinez Velasco Fernando Tamez. The FDA recommends it. Salman KE, Altunay IK, Kucukunal NA, Cerman AA. These effects were already evident after 3 months' treatment and further improved in those patients who continued treatment to month 6. Nanoxidil, on the other hand, is new on the scene, and there have been comparatively few studies on it. Consult with your doctor before making any changes to your daily routines or diet. Regardless, nanoxidil is readily available in stores as it is considered to be more of a cosmeceutical agent than a pharmaceutical drug. As an Amazon Associate this website earns from qualifying purchases. Especially cat owners who live in a household where someone uses minoxidil. Just keep your cat out of the bathroom while you apply it so they don't drink up minoxidil-water from the sink, and don't let them lick your hair or play with it until it dries and you . Additional drugs such as dopamine may be required to help maintain the blood pressure. This reduced strength minoxidil comes in a 5 milliliter bottle. You must consult your own medical professional. It will likely serve as an adenosine 5'-triphosphate-sensitive potassium channel opener with noteworthy effects in circulation and oxygen and nutrient delivery. In rare cases, this genetic mutation is known to occur even when the individual in question has not yet begun the process of going bald. It is not well known that minoxidil may have a unique toxicity to cats. The difference in concentration doesnt mean a difference in results. The hair follicle is damaged by stress, poor nutrition, UV radiation and some drugs. Heres a quick breakdown of the advantages and disadvantages of each: Right now, we believe minoxidil to be the easiest to recommend of the two. Creatine occurs naturally in the human body. Do you put it on before you sleep and do you let the cats sleep with you too? They branded this new version 1988 as Rogaine. Ultimately, nanoxidil has one less carbon atom and two fewer hydrogen atoms. January 25, 2021 - Updated on February 24, 2022. A; PBMA. Minoxidil contains propoxphene and it is this ingredient that works as a vasodilator. Minoxidil is mainly absorbed by the system through the scalp and through the topical application. Minoxidil. lightheadedness. Efficacy and safety of 5% minoxidil topical foam in male pattern hair loss treatment and patient satisfaction. If Minoxidil was ingested; blood tests may reveal abnormal electrolyte concentrations, dehydration, or elevation in muscle enzymes. Cats must never come into contact with the actual minoxidil bottle or canister. Theres also reason to believe that minoxidil may act as a nitric oxide agonist, causing your weak follicles in the telogen phase to fall out (a process we call shedding). window.dataLayer = window.dataLayer || [];function gtag(){dataLayer.push(arguments);}gtag('js', new Date());gtag('set', 'developer_id.dZjQwMz', true);gtag('config', 'UA-44942717-1'); Minoxidil is a commonly used topical treatment for men and women with hair loss. However, the stronger the solution, the more likely it is to grow back your hair. Minoxidil is often recommended as a first line treatment for male pattern baldness, thats why you may see a lot of commercials for it. } An animal-based trial conducted in 2009 demonstrated that the topical use of 5% nanoxidil was effective in promoting hair growth in the dorsal area . This is where nanoxidil comes in. The best preventive care is to give your cat medications only if directed by your veterinarian.Medications that may be safe for people can be fatal to pets.Also, make sure that all medications are kept out of the reach of inquisitive pets. Death occurred in 12.9% of cats that developed clinical signs after the pet owner's minoxidil use. Phase II Study to Evaluate Efficacy and Safety of SPECTRAL.DNC-N Topical Solution For the Treatment of Mild to Moderate Androgenic Alopecia. - BEGIN YOUR TELEMEDICINE CONSULT NOW, PLANNING YOUR FIRST VISIT WITH DR. DONOVAN, FREQUENTLY ASKED QUESTIONS ABOUT THE FIRST VISIT, FREQUENTLY ASKED QUESTIONS ABOUT SUBSEQUENT APPOINTMENTS, INFORMATION ON FOLLOW UP APPOINTMENT FREQUENCY, SEND US DOCUMENTS AND PHOTOS (SECURE UPLOAD LINK), Referral Information & Form for Physicians, Dr. Donovan's Hair Loss Articles (2011-2023), SIGN UP TO RECEIVE DR. DONOVAN'S ARTICLES. Im a big advocate for having a great work/life balance. How oddnever heard of this the entire time I have been on this site. Also, even when it does work, it may not work to the extent that you want it to, causing it to be an ineffective hair loss treatment. The primary difference between the two is how long they last in your system. As someone suffering from hair loss himself, Christopher began his extensive research journey. The most common form of minoxidil is typically used as a treatment for male pattern baldness. (4)(5) However, it is not effective for everyone. We also appreciate that they include botanical supplements in their nanoxidil formula to maximize its efficacy. It widens the hair follicles and allows more blood to enter the follicles, stimulating the production of new hair. numbness or tingling of hands, feet, or face. Excessive hair loss, medically known as telogen effluvium, is a common problem among people, especially in old age. Minoxidil works well for hair loss but it has to be applied to the area twice a day. This is also the time when minoxidil and nanoxidil are effective at helping your hair grow. Between the two, Minoxidil has been around longer. They revealed that their innovative product, clascoterone. } In later studies to test Lonitens potential to treat hypertension, study administrators found unexpected hair growth to be a common and baffling side effect. I am Dr. Gotthelf. I read about this awhile back. Expect your veterinarian to recommend hospitalization with continuous intravenous fluids. During a three-month clinical trial of Nanoxidil with human subjects, no side effects were observed. This particular design has emerged as the most modernized option among the bunch of new hair growth device. First of all, I don't put it on before sleeping and I don't even lie down when I have it on. Subsequently, minoxidil ointment was approved by the FDA as a remedy for hair loss. :mrgreen: Well it got me first! A complete catagen hair implant takes about 2 hours, but it may take more time if you have a bald scalp. It wakes up the dormant hair follicles, and provides the lost nutrients. The first cat was a 3 year old cat had only one drop applied to an area of hair loss. You can read more about DS Laboratories in our complete review. For instance, the phase II study from DS Healthcare Group Inc. is evaluating the efficacy and safety of nanoxidil in the treatment of mild to moderate androgenic alopecia. The few side effects that you might have are primarily mild include headaches, dry skin, dizziness, itchiness, redness, and hair growth in other places. You can also enjoy 50% off your first 3 months of minoxidil. The exact way that this medicine works is not known. The good news is that market trials and patient data have already revealed that nanoxidil has fewer to no side effects compared to minoxidil. h1.qusth1 { However, it is not well known among users of minoxidil that minoxidil may have a unique toxicity to cats. (2019).